The Center for Cardiometabolic Science was established as the Diabetes and Obesity Center. The Diabetes and Obesity Center was founded in 2008 by Dr. Aruni Bhatnagar. He served as Director until 2019, when Dr. Steven Jones assumed the Director role. The Center's name change became effective in 2022.

The Center is the oldest and largest Center in the Envirome Institute. The Center is also the single greatest concentration of cardiovascular investigators at the University of Louisville.

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Email: CardioMetaboSci@Louisville.edu