Center for Cardiometabolic Science

...where cardiovascular mysteries are solved.

Exercise and Metabolic Cages


Exercise Systems  The Center has three Columbus Instruments six-lane rodent treadmills with software-controlled capabilities. The Center also maintains 50 in-cage voluntary exercise mouse running wheels equipped with VitalView activity software for 24 h automated recording. In addition to forced and voluntary exercise systems, the Core maintains two 15-gallon tanks for swimming exercise in mice.

Metabolic/Behavioral Phenotyping System The Center has an 8-cage behavioral and metabolic phenotyping Promethion Core system (Sable Systems International) outfitted with voluntary wheels and programmable access to food and water. The system is equipped with a stable isotope gas analyzer for analysis of nutrient utilization and the system operates within an environmentally controlled cabinet with programmed passcode protected accessibility. Using Promethion Live software, real-time data for each parameter of every cage can be viewed, allowing users to make key decisions at any time, from any place. We also have a complete TSE PhenoMaster/LabMaster Metabolic Chamber system to monitor individual mouse metabolic functions including indirect calorimetry (O2 consumption, CO2production, RER), food intake, water consumption, and total activity (ambulatory and fine motor activity in X-axis).


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