Our Mission
Combatting disease. Transforming health.
Cardiometabolic disease is the leading cause of morbidity and mortality. This challenge demands integrative, mechanism-driven solutions. At our Center, we unite investigators across cardiovascular biology, metabolism, immunology, genomics, and physiology to address the most pressing questions for human health.
Our approach is mechanistic, collaborative, and translational.
Integrated, Systems-Level Science
We move beyond single-organ silos to study physiological function across interconnected systems.
Advanced Research Platforms
Our shared cores provide standardized, high-quality phenotyping, imaging, metabolic, and molecular capabilities.
Collaborative Culture
Faculty, staff, trainees, and other partners work together in a highly interactive, team-science environment.
Translational Impact
Our work informs therapeutic development, biomarker discovery, and disease modeling relevant to human health.
We move beyond single-organ silos to study physiological function across interconnected systems.
Advanced Research Platforms
Our shared cores provide standardized, high-quality phenotyping, imaging, metabolic, and molecular capabilities.
Collaborative Culture
Faculty, staff, trainees, and other partners work together in a highly interactive, team-science environment.
Translational Impact
Our work informs therapeutic development, biomarker discovery, and disease modeling relevant to human health.
Cardiovascular Biology
Spanning conventional studies of heart structure/function to include modern aspects of heart failure.
Inflammation & Immunometabolism
Deciphering subtle changes in immune responses and contextualizing substrate-level changes that drive inflammation.
Metabolism & Obesity
Understanding fundamental aspects of intermediary metabolism and factors contributing to obesity.
Exercise & Physical Activity
Investigating how physical activity shapes molecular pathways that enhance resilience and support cardiometabolic health.
Heart–Kidney Crosstalk
Leveraging this central axis to elucidate adaptations for health and mechanisms of dysregulation in disease.
Precision & Systems Biology
Using advanced informatics techniques for sequencing and mass spectrometry data to deliver insights regarding health and disease.
Spanning conventional studies of heart structure/function to include modern aspects of heart failure.
Inflammation & Immunometabolism
Deciphering subtle changes in immune responses and contextualizing substrate-level changes that drive inflammation.
Metabolism & Obesity
Understanding fundamental aspects of intermediary metabolism and factors contributing to obesity.
Exercise & Physical Activity
Investigating how physical activity shapes molecular pathways that enhance resilience and support cardiometabolic health.
Heart–Kidney Crosstalk
Leveraging this central axis to elucidate adaptations for health and mechanisms of dysregulation in disease.
Precision & Systems Biology
Using advanced informatics techniques for sequencing and mass spectrometry data to deliver insights regarding health and disease.
Deliver interdisciplinary science.
Grow funding from the NIH.
Expand industry and foundation partnerships.
Train Where Discovery Happens
The Center offers rigorous training, strong mentorship, and access to cutting-edge science. Contact the Director to discuss opportunities and next steps.